Science

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The proof is in the data.

MITA is the first and only language therapy application supported by clinical data.

In a 3-year clinical trial of 6,454 children with autism, language score in children who engaged with MITA has increased to levels that were 120% higher than in children with similar initial evaluations. This difference was statistically significant (p<0.0001). The manuscript describing the study has been published in the journal Healthcare.

The FDA has granted MITA a breakthrough device designation (Q210093). We are working with the FDA to establish a pathway for MITA to become a reimbursable digital medicine.

 

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  • Receptive and expressive language phenotyping in over 62,000 autistic Individuals
    This study identified three receptive language phenotypes—Command, Modifier, and Syntactic—and four expressive phenotypes—Nonspeaking, Single-Word, Single-Sentence, and Multi-Sentence—in autistic individuals. These findings suggest that the traditional tripartite classification may not adequately capture the heterogeneity of language profiles commonly observed in clinical practice. In contrast, a two-dimensional framework that separately reports receptive and expressive language phenotypes may offer a more accurate and clinically meaningful characterization of communicative functioning.
    npj Science of learning     (2026)
  • Do grammatical variations between languages influence early language acquisition in autistic individuals?
    This study is the first to investigate whether a child’s native language influences the developmental trajectory of language acquisition in children with ASD. Although languages differ significantly in grammar, syntax, and morphological complexity, our analysis revealed no statistically significant differences in receptive or expressive language development among children with ASD across different language groups.
    Language and Health (2    025)
  • How one small tribe conquered the world 70,000 years ago
    Genetic evidence indicates that most humans descend from a single tribe that 70,000–40,000ya rapidly replaced the entire Eurasian population while also gradually expanding within Africa. This rapid expansion of one tribe is supported by five lines of genetic evidence: (1) Y-chromosome data tracing most non-African male lineages to haplogroup CT 70,000ya; (2) mitochondrial DNA, which shows that most non-Africans descend from haplogroup L3 and its M and N branches that spread across Eurasia 70,000ya; (3) nuclear DNA analyses confirming that all non-Africans derive from a single migration event 70,000–50,000ya; (4) evidence of genetic bottleneck; (5) 2% Neanderthal DNA in all non-Africans, showing interbreeding before Eurasian dispersal. What social, cognitive, or technological advantage enabled this extraordinary expansion? The discovery of three discrete levels of language comprehension in modern individuals suggests the possibility that this ancestral tribe experienced a leap from the Modifier to the Syntactic Phenotype, unlocking unprecedented capacities for coordination, strategizing, and deception.
    Evolutionary Linguistic Theory (2    026)

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The driving force behind ImagiRation puzzles is the Prefrontal Synthesis theory, developed by the company’s co-founder Dr. Vyshedskiy. If you’re interested in reading more about this theory and Dr. Vyshedskiy’s research, please read “The Evolution of Language.”


INDEPENDENT SCIENTIFIC RESEARCH

  • In 4-year-old children computerized training with puzzles that gradually increased in difficulty significantly improved their fluid intelligence compared to a control group trained on puzzles that did not increase in difficulty over time. Reference: Bergman Nutley, Sissela, et al. “Gains in fluid intelligence after training non‐verbal reasoning in 4‐year‐old children: a controlled, randomized study.”– Developmental science 14.3 (2011): 591-601.
  • In children aged 7 to 9, reasoning training with puzzles similar to ImagiRation puzzles increased “performance IQ by an average of 10 points, with four of the 17 children showing gains of over 20 points.” Reference: Mackey, Allyson P., et al. “Differential effects of reasoning and speed training in children.”– Developmental Science 14.3 (2011): 582-590.
  • There is also significant evidence of long-term benefits of cognitive training. Reference: Jaeggi, Susanne M., et al. “Short-and long-term benefits of cognitive training.”– Proceedings of the National Academy of Sciences 108.25 (2011): 10081-10086.